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Alzheimer
Spray Cure |
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In 1906, Alzheimer’s disease was first discovered after
observing the neuropathological anatomy of a 55-year old woman’s brain. For
years after that, the disease has been a constant focus of various studies
in both psychiatry and neuropathology. Yet now roughly a hundred years
later, scientists still have not found the cause and cure of this brain
disorder. Furthermore, there is no real treatment available.
So what is medical science doing with Alzheimer’s research? And how far are
we from the time the concept of Alzheimer’s disease was first introduced to
us by Dr. Alois Alzheimer?
The answer can be found in scientists’ new discovery of a treatment option
in the form of one very simple-looking nasal spray.
Nose drops anyone?
Who would have thought? All those years of research, a century of medical
history, and tons and tons of scientific paperwork to do…who would have
thought it would all boil down to this: an nasal Alzheimer spray cure. Well,
granted that this Alzheimer spray cure is not really a cure, in the sense
that it would not put an effective halt to the disease, but it does help
stop the disease from further progression.
In a study published in 2005 in the Journal of Clinical Investigation,
scientist Howard Weiner, at Brigham and Women’s Hospital in Boston, US, and
his colleagues have discovered the new Alzheimer spray cure. The vaccine,
introduced nasally via nose drops, has been shown to clear plaques from the
brains of affected mice.
Previous attempts at producing a therapeutic vaccine against Alzheimer’s
disease all involved antibodies that act against beta amyloid, the protein
that occurs naturally in our body and is widely considered as the potential
cause of the disease.
In many cases of Alzheimer’s, patients show plaques in the brain,
purportedly caused by these beta amyloid proteins. Scientists believed that
by getting rid or reducing the levels of beta amyloid content in the brain
would reverse the damage caused by the plaques. However, the antibody
approach to curing Alzheimer’s was halted after 15 out of 360 volunteers in
the studies developed swelling in the brain.
Now, the Alzheimer spray cure developed by Howard Weiner and his team could
be the answer many patients of this brain disorder are looking for.
“Sometimes, Inflammation is Good.”
The study on the Alzheimer spray cure came about after Weiner discovered the
intriguing fact that brain inflammation in the earlier trial coincided with
exceptional clearance of beta amyloid. A few experiments later, Weiner found
that mice with Alzheimer’s also cleared the beta amyloid from their brains
after they were subjected to treatment that caused them to develop multiple
sclerosis-like brain inflammation.
“Sometimes, inflammation is good,” he was reported to have said.
Later on, it was discovered that inflammation caused the brain to activate
its specialized cells called microglia, which was responsible for ingesting
the beta amyloid. This led them to the Alzheimer spray cure, the
pharmacological make up of which included a combination of glatiramer
acetate (Copaxone), an approved MS drug that acts as a decoy for errant
immune system attacks, and Protollin, an adjuvant that stimulates innate
immunity.
The Alzheimer spray cure is set to be tested on humans in 2006. |
| This article
is provided courtesy of Roxanne Courtmanch. Please visit
www.thehelpingcircle.com for more articles on Alzheimers
as well as many other topics that may be of interest to you. |
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